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Symbol
Name
ID
Lta
lymphotoxin A
MGI:104797
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Diabetes mellitus
Type II diabetes mellitus
Elevated sweat chloride
Exocrine pancreatic insufficiency
Pancreatitis
Increased circulating free T3
Increased circulating free T4 concentration
Decreased thyroid-stimulating hormone level
Abnormality of the adrenal glands
Goiter
Graves disease
Disease(s) Associated with LTA
coronary artery disease
cystic fibrosis
Graves' disease
leprosy
type 1 diabetes mellitus
type 2 diabetes mellitus

Mouse Phenotypes
abnormal pancreatic islet morphology
abnormal thymus epithelium morphology
abnormal thymus medulla morphology
small thymus medulla
insulitis
periinsulitis
Availability Mouse Genotype
Ltatm1Dch/Ltatm1Dch
Ltatm1Jods/Ltatm1Jods
Tg(Ins2-Lta)#Flv/0

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory